Research Archive

Peruse the scientific research and scholarly journal articles cited in our Healing Knowledge Base.

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Ablon G. Combination 830-nm and 633-nm light-emitting diode phototherapy shows promise in the treatment of recalcitrant psoriasis: preliminary findings . Photomed Laser Surg. 2010 Feb;28(1):141-6. doi: 10.1089/pho.2009.2484.

Abou-Hala AZ, Barbosa DG, Marcos RL, et al. Effects of the Infrared Lamp Illumination during the Process of Muscle Fatigue in Rats . RAZ ARCH BIOL TECHNOL. 01/2007; 50(3). doi: 10.1590/S1516-89132007000300006.

Airan LE, Hruza G. Current lasers in skin resurfacing . Facial Plast Surg Clin North Am. 2005 Feb;13(1):127-39.

Alster TS, Tanzi EL. Cellulite treatment using a novel combination radiofrequency, infrared light, and mechanical tissue manipulation device . J Cosmet Laser Ther. 2005 Jun;7(2):81-5.

American Cancer Society. Cancer Facts & Figures 2016 . Atlanta: American Cancer Society. 2016.

American Cancer Society. Hyperthermia to Treat Cancer . Atlanta: American Cancer Society. 2013.

American Society for Testing and Materials. Reference Solar Spectral Irradiance: Air Mass 1.5 . ASTM. Sep 28, 2013.

Applegate LA, Scaletta C, Panizzon R, Frenk E, Hohlfeld P, Schwarzkopf S. Induction of the putative protective protein ferritin by infrared radiation: implications in skin repair . Int J Mol Med. 2000 Mar;5(3):247-51.

Atanackovic D, Nierhaus A, Neumeier M, Hossfeld DK, Hegewisch-Becker S. 41.8 degrees C whole body hyperthermia as an adjunct to chemotherapy induces prolonged T cell activation in patients with various malignant diseases . Cancer Immunol Immunother. Oct 18 2002;51(11-12):603.

Avci P, Gupta A, Sadasivam M, Vecchio D, Pam Z, Pam N, Hamblin MR. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring . Semin Cutan Med Surg. 2013 Mar;32(1):41-52.

Azeemi S, Raza M. A Critical Analysis of Chromotherapy and Its Scientific Evolution . Evidence-Based Complementary and Alternative Medicine. Vol. 2, no. 4, pp. 481-488, 2005. doi :10.1093/ecam/neh137.


Barni S, Bertone V, Silvotti MG, Freitas I, Mathé G, Pontiggia P. Lysosomal exocytosis induced by hyperthermia: a new model of cancer death. III. effect on liver metastasis . Biomed Pharmacother. 1996;50:79-84.

Barolet D, Boucher A. LED photoprevention: reduced MED response following multiple LED exposures . Lasers Surg Med. 2008 Feb;40(2):106-12. doi: 10.1002/lsm.20615.

Barolet D, Boucher A. Prophylactic low-level light therapy for the treatment of hypertrophic scars and keloids: a case series . Lasers Surg Med. 2010 Aug;42(6):597-601. doi: 10.1002/lsm.20952.

Barolet D, Roberge CJ, Auger FA, Boucher A, Germain L. Regulation of skin collagen metabolism in vitro using a pulsed 660 nm LED light source: clinical correlation with a single-blinded study . J Invest Dermatol. 2009 Dec;129(12):2751-9. doi: 10.1038/jid.2009.186. Epub 2009 Jul 9.

Barton ER, Morris L, Musaro A, Rosenthal N, Sweeney HL. Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice . J Cell Biol. 2002 Apr 1;157(1):137-48. Epub 2002 Apr 1.

Beauvoit B, Kitai T, and Chance B. Contribution of the mitochondrial compartment to the optical properties of the rat liver: a theoretical and practical approach Biophys J. 1994 Dec;67(6):2501-10.

Bello-Silva MS, de Freitas PM, Aranha AC, Lage-Marques JL, Simões A, de Paula Eduardo C. Low- and high-intensity lasers in the treatment of herpes simplex virus 1 infection . Photomed Laser Surg. 2010 Feb;28(1):135-9. doi: 10.1089/pho.2008.2458.

Bibikova A, Oron U. Promotion of muscle regeneration in the toad (Bufo viridis) gastrocnemius muscle by low-energy laser irradiation. Anat Rec. 1993 Mar;235(3):374-80.

Bjordal JM, Johnson MI, Iversen V, Aimbire F, Lopes-Martins RA. Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials . Photomed Laser Surg. 2006 Apr;24(2):158-68.

Bjordal JM, Lopes-Martins RA, Joensen J, et al. A systematic review with procedural assessments and meta-analysis of Low Level Laser Therapy in lateral elbow tendinopathy (tennis elbow) . BMC Musculoskeletal Disorders. 2008;9:75. doi:10.1186/1471-2474-9-75.

Branham GH, Thomas JR. Rejuvenation of the skin surface: chemical peel and dermabrasion . Facial Plast Surg. 1996 Apr;12(2):125-33.

Burd R, Dziedzic TS, Xu Y, Caligiuri MA, Subjeck JR, Repasky EA. Tumor cell apoptosis, lymphocyte recruitment and tumor vascular changes are induced by low temperature, long duration (fever-like) whole body hyperthermia . J Cell Physiol. 1998;177(1):137-147.


Calles C, Schneider M, Macaluso F, Benesova T, Krutmann J, Schroeder P. Infrared A radiation influences the skin fibroblast transcriptome: mechanisms and consequences . J Invest Dermatol. 2010 Jun;130(6):1524-36. doi: 10.1038/jid.2010.9. Epub 2010 Feb 4.

Caruso-Davis MK, Guillot TS, Podichetty VK, Mashtalir N, Dhurandhar NV, Dubuisson O, Yu Y, Greenway FL. Efficacy of low-level laser therapy for body contouring and spot fat reduction . Obes Surg. 2011 Jun;21(6):722-9. doi: 10.1007/s11695-010-0126-y.

Castex-Rizzi N, Lachgar S, Charvéron M, Gall Y. Implication of VEGF, steroid hormones and neuropeptides in hair follicle cell responses [Article in French] . Ann Dermatol Venereol. 2002 May;129(5 Pt 2):783-6.

Cecchini MA, Root DE, Rachunow JR, Gelb PM. Chemical exposures at the World Trade Center: Use of the Hubbard sauna detoxification regimen to improve the health status of New York City rescue workers exposed to toxicants . Townsend Lett. 2006; April:58–65.

Centers For Disease Control and Prevention. CDC Lyme Disease Data .

Cherniaev, IuS. Investigation of the permeability of human skin to infrared radiation [Article in Russian] . Gig Sanit. 1965 Dec;30(12):20-4.

Chow LS, Albright RC, Bigelow ML, Toffolo G, Cobelli C, Nair KS. Mechanism of insulin’s anabolic effect on muscle: measurements of muscle protein synthesis and breakdown using aminoacyl-tRNA and other surrogate measures . Am J Physiol Endocrinol Metab. 2006 Oct;291(4):E729-36. Epub 2006 May 16.

Chow RT, Johnson MI, PhD, Lopes-Martins R, Bjordal JM. Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials . Lancet. 2009 Dec 5;374(9705):1897-908. doi: 10.1016/S0140-6736(09)61522-1. Epub 2009 Nov 13.

Christensen SE, Jørgensen OL, et al. Characterization of Growth Hormone Release in Response to External Heating Acta Endocrinol (Copenh). 1984 Nov; 107(3): 295-301.

Christman JV, Gisolfi CV. Heat acclimation: role of norepinephrine in the anterior hypothalamus . J Appl Physiol (1985). 1985 Jun;58(6):1923-8.

Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR. The Nuts and Bolts of Low-level Laser (Light) Therapy . Ann Biomed Eng. 2012 Feb;40(2):516-33. doi: 10.1007/s10439-011-0454-7. Epub 2011 Nov 2.

Clark IA, Vissel B. Inflammation-sleep interface in brain disease: TNF, insulin, orexin . J Neuroinflammation. 2014 Mar 21;11:51. doi: 10.1186/1742-2094-11-51.

Colbert D, MD. Curbing the Toxic Onslaught. Detoxification III . NutriNews, Douglas Laboratories. 2005, Autumn.

Coleman ME, DeMayo F, Yin KC, Lee HM, Geske R, Montgomery C, Schwartz RJ. Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice . J Biol Chem. 1995 May 19;270(20):12109-16.

Cooper CE, Springett R. “Measurement of Cytochrome Oxidase and Mitochondrial Energetics by Near-Infrared Spectroscopy . Philos Trans R Soc Lond B Biol Sci. Jun 29, 1997; 352(1354): 669–676. doi:  10.1098/rstb.1997.0048.

Costa RJ, Crockford MJ, Moore JP, Walsh NP. Heat acclimation responses of an ultra-endurance running group preparing for hot desert-based competition . Eur J Sport Sci. 2014;14 Suppl 1:S131-41. doi: 10.1080/17461391.2012.660506. Epub 2012 Mar 19.

Cunliffe WJ, Goulden V. Phototherapy and acne vulgaris . Br J Dermatol. 2000 May;142(5):855-6.


de Jesus JF, Spadacci-Morena DD, dos Anjos Rabelo ND, Pinfildi CE, Fukuda TY, Plapler H. Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon . Lasers Med Sci. 2015 Jan;30(1):153-8. doi: 10.1007/s10103-014-1636-y. Epub 2014 Jul 29.

DeBruyne LK, Pinna K, Whitney EN. Nutrition and Diet Therapy . Belmont, CA: Cengage Learning. 8th edition, June 20 2011: 187.

Demura S, Noguchi T, Matsuzawa J. Comparison in the Effect of Linear Polarized Near-Infrared Light Irradiation and Light Exercise on Shoulder Joint Flexibility J Mol Cell Cardiol. Jan 2009; 46(1): 4–14. doi:  10.1016/j.yjmcc.2008.09.707.

Demura S, Yamaji S, Ikemoto Y. Effect of linear polarized near-infrared light irradiation on flexibility of shoulder and ankle joints J Sports Med Phys Fitness. 2002 Dec;42(4):438-45.

Duveau V, Arthaud S, Serre H, Rougier A, Le Gal La Salle G. Transient hyperthermia protects against subsequent seizures and epilepsy-induced cell damage in the rat . Neurobiol Dis. 2005 Jun-Jul;19(1-2):142-9.


Eduardo Cde P, Bezinelli LM, Eduardo Fde P, da Graça Lopes RM, Ramalho KM, Bello-Silva MS, Esteves-Oliveira M. Prevention of recurrent herpes labialis outbreaks through low-intensity laser therapy: a clinical protocol with 3-year follow-up . Lasers Med Sci. 2012 Sep;27(5):1077-83. doi: 10.1007/s10103-011-1019-6. Epub 2011 Nov 16.

Eells JT, Henry MM, Summerfelt P, Wong-Riley MTT, Buchmann EV, Kane M, Whelan NT, and Whelan HT. Therapeutic photobiomodulation for methanol-induced retinal toxicity . Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6): 3439–3444. Published online 2003 Mar 7. doi: 10.1073/pnas.0534746100

Eells JT, Wong-Riley MT, VerHoeve J, Henry M, Buchman EV, Kane MP, Gould LJ, Das R, Jett M, Hodgson BD, Margolis D, Whelan HT. Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy . Mitochondrion. 2004 Sep;4(5-6):559-67.


Falaki F, Nejat AH, Dalirsani Z. The Effect of Low-level Laser Therapy on Trigeminal Neuralgia: A Review of Literature . Journal of Dental Research, Dental Clinics, Dental Prospects. 2014;8(1):1-5. doi:10.5681/joddd.2014.001.

Felsing NE, Brasel JA, Cooper DM. Effect of Low and High Intensity Exercise on Circulating Growth Hormone in Men . J Clin Endocrinol Metab. 1992 Jul;75(1):157-62.

Ferraresi C, Hamblin MR, Parizotto NA. Low-level laser (light) therapy (LLLT) on muscle tissue: performance, fatigue and repair benefited by the power of light . Photonics & lasers in medicine. 2012;1(4):267-286. doi:10.1515/plm-2012-0032.

Fessenden J. Tuning light to kill deep cancer tumors . UMass Medical School Communications. 10/2014.

Frank S, Oliver L, Lebreton-De Coster C, Moreau C, Lecabellec MT, Michel L, Vallette FM, Dubertret L, Coulomb B. Infrared radiation affects the mitochondrial pathway of apoptosis in human fibroblasts . J Invest Dermatol. 2004 Nov;123(5):823-31.

Ftaiti F, Jemni M, Kacem A, Zaouali MA, Tabka Z, Zbidi A, Grélot L. Effect of hyperthermia and physical activity on circulating growth hormone . Appl Physiol Nutr Metab. 2008 Oct;33(5):880-7. doi: 10.1139/H08-073.


Gale GD, Rothbart PJ, Li Y. Infrared therapy for chronic low back pain: a randomized, controlled trial . Pain Res Manag. 2006 Autumn;11(3):193-6.

Gard ZR, Brown EJ. Literature review & comparison studies of sauna/hyperthermia in detoxification: Part I . Townsend Lett. 1992; June:470–478.

Gard ZR, Brown EJ. Literature review & comparison studies of sauna/hyperthermia in detoxification: Part II . Townsend Lett. 1992; July:650–660.

Gard, ZR, Brown EJ. Literature review & comparison studies of sauna/hyperthermia in detoxification: Part III . Townsend Lett. 1992; Aug/Sept.

Garrett AT, Creasy R, Rehrer NJ, Patterson MJ, Cotter JD. Effectiveness of short-term heat acclimation for highly trained athletes . Eur J Appl Physiol. 2012 May;112(5):1827-37. doi: 10.1007/s00421-011-2153-3. Epub 2011 Sep 14.

Gilligan DM, Panza JM, Kilcoyne CM, et al. Contribution of endothelium-derived nitric oxide to exercise-induced vasodilation . Circulation. Dec 1994, Vol 90, No 6.

Goekint M, Roelands B, Heyman E, Njemini R, Meeusen R. Influence of citalopram and environmental temperature on exercise-induced changes in BDNF . Neurosci Lett. 2011 Apr 25;494(2):150-4. doi: 10.1016/j.neulet.2011.03.001. Epub 2011 Mar 6.

Goldberg DJ, Russell BA. Combination blue (415 nm) and red (633 nm) LED phototherapy in the treatment of mild to severe acne vulgaris . J Cosmet Laser Ther. 2006 Jun;8(2):71-5.

Goldmann, H. Kritische und experimentelle Untersuchungen über den sogenannten Ultrarotstar der Kaninchen und den Feuerstar [Text in German] . Arch. Ophthal. Dec 1930; 125: 313-402.

Gomes LE, Dalmarco EM, André ES. The brain-derived neurotrophic factor, nerve growth factor, neurotrophin-3, and induced nitric oxide synthase expressions after low-level laser therapy in an axonotmesis experimental model . Photomed Laser Surg. 2012 Nov;30(11):642-7. doi: 10.1089/pho.2012.3242. Epub 2012 Sep 24.

Gregg C, Shikar V, Larsen P, Mak G, Chojnacki A, Yong VW, Weiss S. White matter plasticity and enhanced remyelination in the maternal CNS . J Neurosci. 2007 Feb 21;27(8):1812-23.

Guillet C, Masgrau A, Walrand S, Boirie Y. Impaired protein metabolism: interlinks between obesity, insulin resistance and inflammation . Obes Rev. 2012 Dec;13 Suppl 2:51-7. doi: 10.1111/j.1467-789X.2012.01037.x.


Ham WT Jr, Mueller HA, Ruffolo JJ Jr, Clarke AM. Sensitivity of the retina to radiation damage as a function of wavelength . Photochem Photobiol. 1979 Apr;29(4):735-43.

Hamblin M. Can osteoarthritis be treated with light? . Arthritis Research & Therapy. 2013, 15:120 doi:10.1186/ar4354.

Hamblin M. Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. AIMS Biophysics.4(3): 337-361. (May 2017); DOI: 10.3934/biophy.2017.3.337.

Hamblin M, Demidova T. Mechanisms of low level light therapy . Proc. SPIE 6140, Mechanisms for Low-Light Therapy. 614001 (Feb 2006); doi:10.1117/12.646294.

Hannuksela M L, Ellahham S. Benefits and Risks of Sauna Bathing Am J Med. 2001 Feb;110(2):118-26.

Healy ML, Gibney J, Russell-Jones DL, Pentecost C, Croos P, Sönksen PH, Umpleby AM. High dose growth hormone exerts an anabolic effect at rest and during exercise in endurance-trained athletes. J Clin Endocrinol Metab. 2003 Nov;88(11):5221-6.

Ho KY, Veldhuis JD, Johnson ML, et al. Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man . Journal of Clinical Investigation. 1988;81(4):968-975.

Hopkins JT, McLoda TA, Seegmiller JG, David Baxter G. Low-Level Laser Therapy Facilitates Superficial Wound Healing in Humans: A Triple-Blind, Sham-Controlled Study Journal of Athletic Training. 2004;39(3):223-229.


Ibe O, Morency E, Sosa P,Burkow-Heikkinen L. The role of near-infrared light-emitting diodes in aging adults related to inflammation . Healthy Aging Research. 2015, 4:24; 10 April 2015.

Ihsan F R. Low-level laser therapy accelerates collateral circulation and enhances microcirculation . Photomed Laser Surg. 2005 Jun;23(3):289-94.

Imamura M, Biro S, Kihara T, Yoshifuku S, Takasaki K, Otsuji Y, Minagoe S, Toyama Y & Tei C (2001). “Repeated thermal therapy improves impaired vascular endothelial function in patients with coronary risk factors . J Am Coll Cardiol. 2001; 38, 1083–1088.

Issels Immuno-Oncology. Hyperthermia As Used In Cancer Tumor Treatment .


Jang H, Lee H. Meta-Analysis of Pain Relief Effects by Laser Irradiation on Joint Areas . Photomedicine and Laser Surgery. 2012;30(8):405-417. doi:10.1089/pho.2012.3240.


Khazaeli AA, Tatar M, Pletcher SD, Curtsinger JW. Heat-induced longevity extension in Drosophila. I. Heat treatment, mortality, and thermotolerance . J Gerontol A Biol Sci Med Sci. 1997 Jan;52(1):B48-52.

Kihara T, Biro S, Imamura M, Yoshifuku S, Takasaki K, Ikeda Y, Otuji Y, Minagoe S, Toyama Y & Tei C (2002). Repeated sauna treatment improves vascular endothelial and cardiac function in patients with chronic heart failure . J Am Coll Cardiol. 2002; 39, 754–759.

Kihara T, Miyata M, Fukudome T, Ikeda Y, Shinsato T, Kubozono T, Fujita S, Kuwahata S, Hamasaki S, Torii H, Lee S, Toda H, Tei C. Waon therapy improves the prognosis of patients with chronic heart failure . J Cardiol. 2009 Apr;53(2):214-8. doi: 10.1016/j.jjcc.2008.11.005. Epub 2009 Jan 18.

Kim SG, MD, Shin IH, PhD, Choi CH, MD, & Choe JY, MD. Anti-Inflammatory Effect of Near-Infrared Irradiated Cell Culture Media . Korean J Lab Med. 2009 Aug; 29(04) 338-344.

King DS, Costill DL, Fink WJ, Hargreaves M, Fielding RA. Muscle metabolism during exercise in the heat in unacclimatized and acclimatized humans . J Appl Physiol (1985). 1985 Nov;59(5):1350-4.

Kirwan JP, Costill DL, Kuipers H, Burrell MJ, Fink WJ, Kovaleski JE, Fielding RA. Substrate utilization in leg muscle of men after heat acclimation . J Appl Physiol (1985). 1987 Jul;63(1):31-5.

Kligman LH. Photoaging. Manifestations, prevention, and treatment . Clin Geriatr Med. 1989 Feb;5(1):235-51.

Kokura S, Adachi S, Manabe E, Mizushima K, Hattori T, Okuda T, Nakabe N, Handa O, Takagi T, Naito Y, Yoshida N, Yoshikawa T. Whole body hyperthermia improves obesity-induced insulin resistance in diabetic mice . Int J Hyperthermia. 2007 May;23(3):259-65.

Koltyn KF, Robins HI, Schmitt CL, Cohen JD, Morgan WP. Changes in mood state following whole-body hyperthermia . Int J Hyperthermia. 1992 May-Jun;8(3):305-7.

Kuennen M, Gillum T, Dokladny K, Bedrick E, Schneider S, Moseley P. Thermotolerance and heat acclimation may share a common mechanism in humans . American Journal of Physiology – Regulatory, Integrative and Comparative Physiology. 2011;301(2):R524-R533. doi:10.1152/ajpregu.00039.2011.

Kukkonen-Harjula K, Oja P, Laustiola K, Vuori I, Jolkkonen J, Siitonen S, Vapaatalo H. Haemodynamic and hormonal responses to heat exposure in a Finnish sauna bath . Eur J Appl Physiol Occup Physiol. 1989;58(5):543-50.


Laatikainen T, Salminen K, Kohvakka A, Pettersson J. Response of plasma endorphins, prolactin and catecholamines in women to intense heat in a sauna . Eur J Appl Physiol Occup Physiol. 1988;57(1):98-102.

Lan CC, Wu CS, Chiou MH, Chiang TY, Yu HS. Low-energy helium-neon laser induces melanocyte proliferation via interaction with type IV collagen: visible light as a therapeutic option for vitiligo . Br J Dermatol. 2009 Aug;161(2):273-80. doi: 10.1111/j.1365-2133.2009.09152.x. Epub 2009 Apr 30.

Lan CC, Wu CS, Chiou MH, Hsieh PC, Yu HS. Low-energy helium-neon laser induces locomotion of the immature melanoblasts and promotes melanogenesis of the more differentiated melanoblasts: recapitulation of vitiligo repigmentation in vitro . J Invest Dermatol. 2006 Sep;126(9):2119-26. Epub 2006 May 11.

Landthaler M, Haina D, Waidelich W. Treatment of zoster, post-zoster pain and herpes simplex recidivans in loco with laser light [Article in German] . Fortschr Med. 1983 Jun 9;101(22):1039-41.

Laukkanen T, Hassan Khan H, Zaccardi F, Laukkanen J. Association Between Sauna Bathing and Fatal Cardiovascular and All-Cause Mortality Events . JAMA Intern Med. February 23, 2015. doi:10.1001/jamainternmed.2014.8187.

Leavitt M, Charles G, Heyman E, Michaels D. HairMax LaserComb laser phototherapy device in the treatment of male androgenetic alopecia: A randomized, double-blind, sham device-controlled, multicentre trial . Clin Drug Investig. 2009;29(5):283-92. doi: 10.2165/00044011-200929050-00001.

Lee SY, Park KH, Choi JW, Kwon JK, Lee DR, Shin MS, Lee JS, You CE, Park MY. A prospective, randomized, placebo-controlled, double-blinded, and split-face clinical study on LED phototherapy for skin rejuvenation: clinical, profilometric, histologic, ultrastructural, and biochemical evaluations and comparison of three different treatment settings . J Photochem Photobiol B. 2007 Jul 27;88(1):51-67. Epub 2007 May 1.

Lee SY, You CE, Park MY. Blue and red light combination LED phototherapy for acne vulgaris in patients with skin phototype IV . Lasers Surg Med. 2007 Feb;39(2):180-8.

Lecker SH, Goldberg AL, Mitch WE. Protein degradation by the ubiquitin-proteasome pathway in normal and disease states . J Am Soc Nephrol. 2006 Jul;17(7):1807-19. Epub 2006 May 31.

Leppäluoto J, Huttunen P, Hirvonen J, Väänänen A, Tuominen M, Vuori J. Endocrine effects of repeated sauna bathing . Acta Physiol Scand. 1986 Nov;128(3):467-70.

Lithgow GJ, White TM, Melov S, Johnson TE. Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress . Proceedings of the National Academy of Sciences of the United States of America. 1995;92(16):7540-7544.

Liu W, Wang DR, Cao YL. TGF-beta: a fibrotic factor in wound scarring and a potential target for anti-scarring gene therapy . Curr Gene Ther. 2004 Mar;4(1):123-36.

Liu XL, Ma F, Zhou CX, Huang M, Gong HY, Xie GY, Hu CH. Therapeutic effect of whole body hyperthermia combined with chemotherapy in patients with advanced cancer [Article in Chinese] . Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2006 Jun;31(3):350-2.

Louard RJ, Fryburg DA, Gelfand RA, Barrett EJ. Insulin sensitivity of protein and glucose metabolism in human forearm skeletal muscle . Journal of Clinical Investigation. 1992;90(6):2348-2354.

Lundgren J, Smith ML, Blennow G, Siesjö BK. Hyperthermia aggravates and hypothermia ameliorates epileptic brain damage . Exp Brain Res. 1994;99(1):43-55.

Luo L, Sun Z, Zhang L, Li X, Dong Y, Liu TC. Effects of low-level laser therapy on ROS homeostasis and expression of IGF-1 and TGF-β1 in skeletal muscle during the repair process . Lasers Med Sci. 2013 May;28(3):725-34. doi: 10.1007/s10103-012-1133-0. Epub 2012 Jun 20.

Lydahl E, Philipson B. Infrared radiation and cataract II. Epidemiologic investigation of glass workers . Acta Ophthalmol (Copenh). 1984 Dec;62(6):976-92.


Maegawa Y, Itoh T, Hosokawa T, Yaegashi K, Nishi M. Effects of near-infrared low-level laser irradiation on microcirculation . Lasers Surg Med. 2000; 27(5): 427-37.

Maniam J, Morris MJ. Voluntary exercise and palatable high-fat diet both improve behavioural profile and stress responses in male rats exposed to early life stress: Role of hippocampus . Psychoneuroendocrinology. 2010. doi:10.1016/j.psyneuen.2010.05.012.

Manjili MH, Wanga XY, Parka J, Macdonalda IJ, Lib Y, Van Schiea RCAA & Subjecka JR. Cancer immunotherapy: stress proteins and hyperthermia . Int J Hyperthermia. 2002;18(6): 506-520.

Medrado AP, Soares AP, Santos ET, Reis SR, Andrade ZA. Influence of laser photobiomodulation upon connective tissue remodeling during wound healing . J Photochem Photobiol B. 2008 Sep 18;92(3):144-52. doi: 10.1016/j.jphotobiol.2008.05.008. Epub 2008 Jul 7.

Meneguzzo DT, Lopes LA, Pallota R, Soares-Ferreira L, Lopes-Martins RÁ, Ribeiro MS. Prevention and treatment of mice paw edema by near-infrared low-level laser therapy on lymph nodes . Lasers Med Sci. 2013 May;28(3):973-80. doi: 10.1007/s10103-012-1163-7. Epub 2012 Aug 23.

Mitsunaga M, Ogawa M, Kosaka N, Rosenblum L T, Choyke P L & Kobayashi H (2011). Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules . Nat Med. Nov 6, 2011; 17(12): 1685–1691. doi: 10.1038/nm.2554.

Möckel F, Hoffmann G, Obermüller R, Drobnik W, Schmitz G. Influence of water-filtered infrared-A (wIRA) on reduction of local fat and body weight by physical exercise . Ger Med Sci. 2006; 4: Doc05.

Moseley PL. “Heat shock proteins and heat adaptation of the whole organism . J Appl Physiol (1985). 1997 Nov;83(5):1413-7.

Moss, R. The Life and Times of John Beard, DSc (1858-1924) . Integr Cancer Ther December 2008 vol. 7 no. 4 229-251.

Muñoz Sanchez PJ, Capote Femenías JL, Díaz Tejeda A, Tunér J. The effect of 670-nm low laser therapy on herpes simplex type 1 . Photomed Laser Surg. 2012 Jan;30(1):37-40. doi: 10.1089/pho.2011.3076. Epub 2011 Nov 2.


Nanni CA, Alster TS. Complications of carbon dioxide laser resurfacing. An evaluation of 500 patients . Dermatol Surg. 1998 Mar;24(3):315-20.

Naito H, Powers SK, Demirel HA, Sugiura T, Dodd SL, Aoki J. Heat stress attenuates skeletal muscle atrophy in hindlimb-unweighted rats . J Appl Physiol (1985). 2000 Jan;88(1):359-63.

Narita M, Khotib J, Suzuki M, Ozaki S, Yajima Y, Suzuki T. Heterologous mu-opioid receptor adaptation by repeated stimulation of kappa-opioid receptor: up-regulation of G-protein activation and antinociception . J Neurochem. 2003 Jun;85(5):1171-9.

Nath KA, Balla G, Vercellotti GM, et al. Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat . Journal of Clinical Investigation. 1992;90(1):267-270.

National Cancer Institute. Hyperthermia in Cancer Treatment . Rockville: National Cancer Institute. 2011.

Niwa Y, Kawahira K and Matsumoto K. Effect of far infrared ray emitting products and stones on human leukocyte functions, lipid peroxidation, the growth of tumor on mice, drug-induced hepatitis rat, and clinical course and serum lipid peroxide levels of rheumatoid arthritis patients [in Japanese] . Japanese Journal of Inflammation. 1996; 16, 425-436.

Ostberg JR, Repasky EA. Emerging evidence indicates that physiologically relevant thermal stress regulates dendritic cell function . Cancer Immunol Immunother. Apr 28, 2005.

Otberg N, Finner AM, Shapiro J. Androgenetic alopecia . Endocrinol Metab Clin North Am. 2007 Jun;36(2):379-98.


Paasch U, Haedersdal M. Laser systems for ablative fractional resurfacing . Expert Rev Med Devices. 2011 Jan;8(1):67-83. doi: 10.1586/erd.10.74.

Pall ML. How can we cure NO/ONOO− cycle diseases? Approaches to curing chronic fatigue syndrome/myalgic encephalomyelitis, fibromyalgia, multiple chemical sensitivity, Gulf War syndrome and possibly many others . Townsend Lett. 2010; Feb/March:75–84.

Papageorgiou P, Katsambas A, Chu A. Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris . Br J Dermatol. 2000 May;142(5):973-8.

Pedersen BK. Muscle as a secretory organ . Compr Physiol. 2013 Jul;3(3):1337-62. doi: 10.1002/cphy.c120033.

Philips. R125 Incandescent Reflector Data Sheet Showing Spectral Emission.

Philips. R125 Incandescent Reflector Data Sheet Showing Tissue Penetration Depth of Wavelengths.

Peoples C, Shaw VE, Stone J, Jeffery G,Baker GE, and Mitrofanis J. Survival of Dopaminergic Amacrine Cells after Near-Infrared Light Treatment in MPTP-Treated Mice ISRN Neurol. 2012; 2012: 850150. doi: 10.5402/2012/850150

Porcella S, Schwan T. Borrelia burgdorferi and Treponema pallidum: a comparison of functional genomics, environmental adaptations, and pathogenic mechanisms . J Clin Invest. 2001;107(6):651–656. doi:10.1172/JCI12484.

Posten W, Wrone DA, Dover JS, Arndt KA, Silapunt S, Alam M. Low-level laser therapy for wound healing: mechanism and efficacy . Dermatol Surg. 2005 Mar;31(3):334-40.


Reisinger E, Wendelin I, Gasser R, Halwachs G, Wilders-Truschnig M, Krejs G. Antibiotics and increased temperature against Borrelia burgdorferi in vitro . Scand J Infect Dis. 1996;28(2):155-7.

Rojas JC, Gonzalez-Lima F. Low-level light therapy of the eye and brain . Eye and Brain. 2011;3:49–67.

Rojas JC, Gonzalez-Lima F. Neurological and psychological applications of transcranial lasers and LEDs . Biochem Pharmacol. 2013 Aug 15;86(4):447-57. doi: 10.1016/j.bcp.2013.06.012. Epub 2013 Jun 24.

Rossi AB, Vergnanini AL. Cellulite: a review . J Eur Acad Dermatol Venereol. 2000(July); 14 (4): 251–62. doi:10.1046/j.1468-3083.2000.00016.x.


Sadick NS. Handheld LED array device in the treatment of acne vulgaris . J Drugs Dermatol. 2008 Apr;7(4):347-50.

Salbaum JM, Cirelli C, Walcott E, Krushel LA, Edelman GM, Tononi G. Chlorotoxin-mediated disinhibition of noradrenergic locus coeruleus neurons using a conditional transgenic approach . Brain Res. 2004 Jul 30;1016(1):20-32.

Satino JL, Markou M. Hair Regrowth and Increased Hair Tensile Strength Using the HairMax LaserComb for Low-Level Laser Therapy . International Journal of Cosmetic Surgery and Aesthetic Dermatology. August 2003, 5(2): 113-117. doi:10.1089/153082003769591209.

Saperstein S, Chen L, Oakes D, Pryhuber G, Finkelstein J. IL-1beta augments TNF-alpha-mediated inflammatory responses from lung epithelial cells . J Interferon Cytokine Res. 2009 May;29(5):273-84. doi: 10.1089/jir.2008.0076.

Sasaki GH, Oberg K, Tucker B, Gaston M. The effectiveness and safety of topical PhotoActif phosphatidylcholine-based anti-cellulite gel and LED (red and near-infrared) light on Grade II-III thigh cellulite: a randomized, double-blinded study . J Cosmet Laser Ther. 2007 Jun;9(2):87-96.

Savard GK, Nielsen B, Laszczynska J, Larsen BE, Saltin B. Muscle blood flow is not reduced in humans during moderate exercise and heat stress . J Appl Physiol (1985). 1988 Feb;64(2):649-57.

Sawhney, MK, Hamblin, MR. Low Level Laser (Light) Therapy (LLLT) for Cosmetic Medicine and Dermatology . Wellman Center for Photomedicine, Mass. Gen. Hospital, Boston, MA & Dept. Dermatology, Harvard Med. School, Boston, MA.

Sawka MN, Wenger BC, Pandolf KB. Thermoregulatory Responses to Acute Exercise‐Heat Stress and Heat Acclimation . Compr Physiol. 2011, Supplement 14: Handbook of Physiology, Environmental Physiology: 157-185. First published in print 1996. doi: 10.1002/cphy.cp040109.

Schiffer F, Johnston AL, Ravichandran C, et al. Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety . Behavioral and Brain Functions : BBF. 2009;5:46. doi:10.1186/1744-9081-5-46.

Schindl A, Neumann R. Low-intensity laser therapy is an effective treatment for recurrent herpes simplex infection. Results from a randomized double-blind placebo-controlled study . J Invest Dermatol. 1999 Aug;113(2):221-3.

Schroeder P, Calles C, Benesova T, Macaluso F, Krutmann J. Photoprotection beyond ultraviolet radiation–effective sun protection has to include protection against infrared A radiation-induced skin damage . Skin Pharmacol Physiol. 2010;23(1):15-7. doi: 10.1159/000257259. Epub 2010 Jan 14.

Scoon GS, Hopkins WG, Mayhew S, Cotter JD. Effect of post-exercise sauna bathing on the endurance performance of competitive male runners . J Sci Med Sport. 2007 Aug;10(4):259-62. Epub 2006 Jul 31.

Selsby JT, Dodd SL. Heat treatment reduces oxidative stress and protects muscle mass during immobilization . Am J Physiol Regul Integr Comp Physiol. 2005 Jul;289(1):R134-9. Epub 2005 Mar 10.

Selsby JT, Rother S, Tsuda S, Pracash O, Quindry J, Dodd SL. Intermittent hyperthermia enhances skeletal muscle regrowth and attenuates oxidative damage following reloading . J Appl Physiol (1985). 2007 Apr;102(4):1702-7. Epub 2006 Nov 16.

Shen RN, Hornback NB, Shidnia H, Shupe RE, Brahmi Z. Whole-body hyperthermia decreases lung metastases in lung tumor-bearing mice, possibly via a mechanism involving natural killer cells J Clin Immunol. 1987 May;7(3):246-53.

Shukla S, Sahu K, Verma Y, Rao KD, Dube A, Gupta PK. Effect of helium-neon laser irradiation on hair follicle growth cycle of Swiss albino mice . Skin Pharmacol Physiol. 2010;23(2):79-85. doi: 10.1159/000265678. Epub 2009 Dec 14.

Singh R, Kølvraa S, Bross P, et al. Anti-Inflammatory Heat Shock Protein 70 Genes are Positively Associated with Human Survival . Current pharmaceutical design. 2010;16(7):796-801.

Sinha RP, Häder DP. UV-induced DNA damage and repair: a review . Photochem Photobiol Sci. 2002 Apr;1(4):225-36.

Sriprachya-Anunt S, Fitzpatrick RE, Goldman MP, Smith SR. Infections complicating pulsed carbon dioxide laser resurfacing for photoaged facial skin . Dermatol Surg. 1997 Jul;23(7):527-35; discussion 535-6.

Srivastava PK. Role of Heat Shock Proteins [Supplement to Article Could Our Own Proteins Be Used to Help Us Fight Cancer?] . Sci Am. 2008(July).

Sumen A, Sarsan A, Alkan H, Yildiz N, Ardic F. Efficacy of low level laser therapy and intramuscular electrical stimulation on myofascial pain syndrome . J Back Musculoskelet Rehabil. 2015;28(1):153-8.

Sylver N. The Holistic Handbook of Sauna Therapy . Center for Frequency Education (2003). ISBN-13: 978-0967249179.


Takema Y, Yorimoto Y, Kawai M, Imokawa G. Age-related changes in the elastic properties and thickness of human facial skin . Br J Dermatol. 1994 Nov;131(5):641-8.

Tanaka Y, Matsuo K, Yuzuriha S. Objective assessment of skin rejuvenation using near-infrared 1064-nm neodymium: YAG laser in Asians . Clinical, Cosmetic and Investigational Dermatology. 2011;4:123-130. doi:10.2147/CCID.S22841.

Tatar M, Khazaeli AA, Curtsinger JW. Chaperoning extended life . Nature. 1997 Nov 6;390(6655):30.

Taoa H, Hwangb S, Marellia B, Ana B, Moreaua J E, Yanga M, Brencklea M A, Kimb S, Kaplana D L, Rogers J A, Omenetto F G. Silk-based resorbable electronic devices for remotely controlled therapy and in vivo infection abatement . PNAS. November 24, 2014, doi: 10.1073/pnas.1407743111.


Van Praag H, Christie BR, Sejnowski TJ, Gage FH. Running enhances neurogenesis, learning, and long-term potentiation in mice . Proceedings of the National Academy of Sciences of the United States of America. 1999;96(23):13427-13431.

Velloso CP. Regulation of muscle mass by growth hormone and IGF-I . British Journal of Pharmacology. 2008;154(3):557-568. doi:10.1038/bjp.2008.153.

Voke, J. Radiation effects on the eye . Optometry Today. 1999; 8:30-35.


Wei Q, Hill WD, Su Y, Huang S, Dong Z. Heme oxygenase-1 induction contributes to renoprotection by G-CSF during rhabdomyolysis-associated acute kidney injury. American Journal of Physiology – Renal Physiology. 2011;301(1):F162-F170. doi:10.1152/ajprenal.00438.2010.

Weiss RA, McDaniel DH, Geronemus RG, Weiss MA, Beasley KL, Munavalli GM, Bellew SG. Clinical experience with light-emitting diode (LED) photomodulation. Dermatol Surg. 2005 Sep;31(9 Pt 2):1199-205.

Whelan HT, Buchmann EV, Dhokalia A, Kane MP,Whelan NT, Wong-Riley M, Eells JT, Gould LJ, Hammamieh R, Das R, Jett M. Effect of NASA Light-Emitting Diode Irradiation on Molecular Changes for Wound Healing in Diabetic Mice. Journal of Clinical Laser Medicine & Surgery. April 2003, 21(2): 67-74. doi:10.1089/104454703765035484.

Wigal SB, Nemet D, Swanson JM, Regino R, Trampush J, Ziegler MG, Cooper DM. Catecholamine response to exercise in children with attention deficit hyperactivity disorder. Pediatr Res. 2003 May;53(5):756-61. Epub 2003 Mar 5.

Wikipedia. Hyperthermia Therapy.

Wikramanayake TC, Rodriguez R, Choudhary S, Mauro LM, Nouri K, Schachner LA, Jimenez JJ. Effects of the Lexington LaserComb on hair regrowth in the C3H/HeJ mouse model of alopecia areata. Lasers Med Sci. 2012 Mar;27(2):431-6. doi: 10.1007/s10103-011-0953-7. Epub 2011 Jul 9.

Wilson L, MD. Cancer Pioneers of the 20th Century. The Center For Development. March 2014.

Wilson L, MD. Lyme Disease. The Center For Development. Sept 2012.

Wilson L, MD. Infrared Sauna Therapy For Cancer. The Foundation for Advancement in Cancer Therapy. 2008.

Wilson L, MD. Pneumonia and Other Respiratory Ailments. The Center For Development. Jan 2010.

Wilson L, MD. Sauna Therapy. The Center For Development. March 2014.

Wilson L, MD . Sauna Therapy for Detoxification and Healing. Prescott, AZ: LD Wilson Consultants, Inc; 2011.

Wilson L, MD. Skin, And Care of Your Skin. The Center For Development. March 2015.

Wilson L, MD. Why Does the Near Infrared Lamp Sauna Have An Extremely Parasympathetic (Healing) EffectThe Center For Development. March 2014.

Wong-Riley M, Liang H, et al. Photobiomodulation Directly Benefits Primary Neurons Functionally Inactivated by Toxins. The Journal of Biological Chemistry. February 11, 2005, 280: 4761-4771. doi: 10.1074/jbc.M409650200.


Xin L, Geller EB, Adler MW. Body temperature and analgesic effects of selective mu and kappa opioid receptor agonists microdialyzed into rat brain. J Pharmacol Exp Ther. 1997 Apr;281(1):499-507.


Yamada PM, Amorim FT, Moseley P, Robergs R, Schneider SM. Effect of heat acclimation on heat shock protein 72 and interleukin-10 in humans. J Appl Physiol (1985). 2007 Oct;103(4):1196-204. Epub 2007 Jul 5.

Yenari MA, Giffard RG, Sapolsky RM, Steinberg GK. The neuroprotective potential of heat shock protein 70 (HSP70). Mol Med Today. 1999 Dec;5(12):525-31.

Yousefi-Nooraie R, Schonstein E, Heidari K, Rashidian A, Pennick V, Akbari-Kamrani M, Irani S, Shakiba B, Mortaz Hejri SA, Mortaz Hejri SO, Jonaidi A. Low level laser therapy for nonspecific low-back pain. Cochrane Database Syst Rev. 2008 Apr 16;(2):CD005107. doi: 10.1002/14651858.CD005107.pub4.

Yu HS, Wu CS, Yu CL, Kao YH, Chiou MH. Helium-neon laser irradiation stimulates migration and proliferation in melanocytes and induces repigmentation in segmental-type vitiligo. J Invest Dermatol. 2003 Jan;120(1):56-64.

Yu W, Naim JO, McGowan M, Ippolito K, Lanzafame RJ. Photomodulation of Oxidative Metabolism and Electron Chain Enzymes in Rat Liver Mitochondria. Photochem Photobiol. 1997 Dec;66(6):866-71.


Zhang C, Wong-Riley M. Expression and regulation of NMDA receptor subunit R1 and neuronal nitric oxide synthase in cortical neuronal cultures: correlation with cytochrome oxidase. J Neurocytol. 1999 Jul;28(7):525-39.

Zhang R, Mio Y, Pratt PF, Lohr N, Warltier DC, Whelan HT, Zhu D, Jacobs ER, Medhora M, Bienengraeber M. Near infrared light protects cardiomyocytes from hypoxia and reoxygenation injury by a nitric oxide dependent mechanismJ Mol Cell Cardiol. 2009 Jan;46(1):4-14. doi: 10.1016/j.yjmcc.2008.09.707.

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